Zoladex breast cancer treatment

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Breast cancer is the most common cancer diagnosed in women today excluding non-melanoma skin cancers. Due to increased awareness and numerous screening programs, more and more patients are being diagnosed with earlier, more treatable cancers Weir et al. Hormonal therapy plays an important role in breast cancer and estrogen specifically is targeted in many of the treatments prescribed.

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Breast cancer patients taking part in an international study were less likely to go through early menopause and more likely to become pregnant and give birth if they took the drug Zoladex goserelin during chemotherapy. The women in the study had operable hormone-receptor-negative breast cancer. Loss of fertility is often a side effect of chemotherapywhich can create treatment challenges for young women with breast cancer.

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What is goserelin Zoladex? How does goserelin work as a treatment for breast cancer? When is goserelin prescribed?

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Zoladex is a hormone therapy. It is classified as an "LHRH agonist. Note: If a drug has been approved for one use, physicians may elect to use this same drug for other problems if they believe it may be helpful. Zoladex may cause short-term within first 2 weeks of treatment increases in testosterone serum levels.

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Tamoxifen and Zoladex chemical name: goserelin are hormonal therapy medicines used to lower the risk of breast cancer coming back recurrence in premenopausal women diagnosed with early-stage, hormone-receptor-positive breast cancer. A study found that tamoxifen and Zoladex work about the same to lower the risk of breast cancer coming back. Estrogen can make hormone-receptor-positive breast cancers grow.

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By getting these injections, more women became pregnant without negatively affecting their health or their chances of surviving their cancer. Ovarian failure is one side effect of chemotherapy, one that carries a heavy burden for women, including infertility, sexual dysfunction, and unpleasant symptoms. Between andinvestigators randomly assigned premenopausal women with hormone receptor—negative breast cancer to receive either standard cyclophosphamide-containing chemotherapy or standard chemotherapy plus goserelin.

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Read about goserelin, how you have it and other important information about taking this hormone therapy drug for breast cancer. Goserelin is also known by its brand name Zoladex. It is a type of hormone therapy called a luteinising hormone LH blocker.

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If you're struggling to find what you need, call our Support line on 7 days a week, 8am-8pm. Goserelin is a hormonal therapy drug used to treat breast cancer. It can be given alone or with other types of treatment.

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Study record managers: refer to the Data Element Definitions if submitting registration or results information. The duration of study medication along with the follow-up will be 18 months, or until disease recurrence,or discontinuation of study therapy as a result of an adverse event, a patient's request, or an investigator's decisionfurther treatment will be at investigator's discretion. During the study period, contralateral mammograms and transvaginal ultrasound will be undertaken at baseline and after 6, 12 and 18 months of study medications. Mammographic density assessment will be undertaken by a single radiologist.

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